How Long Do Shrooms Take to Kick

How Long Do Shrooms Take to Kick

Magic mushroom’s wonderful attributes are from the psychoactive chemicals that it bears. Those substances directly go to the bloodstream that is connected to the brain’s serotonin receptor. 

Shrooms contain psilocybin and psilocin. As you want to find the answer to the question ‘How long do shrooms take to kick?’, you might want to be introduced to these substances.


It is the psychoactive substance that is a chemical precursor for psilocin. After you swallow the magic mushroom, it will be broken down by the body slowly.

Then psilocybin and psilocin are released in your digestive tract. Shroom only has a little amount of psilocin than the present psilocybin in it.

When the absorption takes place, psilocin proceeds first to the bloodstream before heading to the brain. There’s an extra metabolic process called dephosphorylation that converts psilocybin to psilocin.

Psilocybin is like a chain element with a structure that is not different from that of psilocin. 

When the shroom is consumed orally, psilocybin is broken down by Alkaline Phosphate. This enzyme gets rid of some of the chemical structures, which are oxygen, phosphorus, and hydrogen, or the phosphate group. 

Once the dephosphorylation is completed, psilocin is ready to enter the bloodstream. This process takes half an hour or an hour to take place, so you have to wait around this duration to feel the effects.


When psilocin has made its way to the bloodstream, it proceeds to unite with serotonin receptors. Serotonin’s job is being a neurotransmitter, and it can control a person’s mood. 

Psilocin has a similar structure with serotonin, so it connects with its receptor. The trip begins at this stage.

The heartbeat becomes faster than normal, and your senses become acute. It makes you find an overwhelming feeling of tranquility and wellness. 

These things happen as psilocin and serotonin receptors interact with each other. The different effects take place as receptors are located in different locations of your body.

Receptors in your cerebral cortex that work with psilocin will affect your emotional state. 

Psilocin is also called a tryptamine alkaloid, which is considered an organic compound. It is composed of hydrogen and carbon, and it is created by various types of fungus. 

The human body releases tryptamine like serotonin. The chemicals on both substances have hydrogen, nitrogen, oxygen, and carbon. The same features allow psilocin to work as a partial antagonist.

These partial antagonists can bind receptors based on the chemical similarities with the neurotransmitters that they replace. The metabolism of psilocin occurs after the moment of peak interaction. The effects tend to wear off at this moment.

When the body lets go of the psilocin, serotonin adjusts its receptors, so the feeling of coming down happens. 

Psilocybin and psilocin are both psychedelics, but the latter is unstable. It’s the reason why its presence in the mushroom is cut down by heat and light.

So psilocybin is converted first to enter your body, and scientists use it to study magic mushrooms. 

Metabolism of Psilocybin

Psilocybin is broken down to turn into psilocin with a matter of 20 to 40 minutes. This information is given by the Drug Metabolism Reviews journal released in 2017. 

You feel the effects as the psilocin amount increased in the bloodstream. The peak of the effects happens an hour and a half after you consume the shroom. Then, this substance slowly disappears from your bloodstream, so you will feel the effects are also fading.

The elimination of the half-life of psilocybin is 160 minutes. While on the side of psilocin, it takes 50 minutes. 

Ninety-five percent of psilocybin goes out of the body for about 13 hours. On the side of psilocin, 95 percent of it also leaves the body but after four hours. 

They are considered as the average time. Actual time for each person varies due to some factors that interfere with the process. 

Body Abilities in Metabolizing Psilocybin 

Consumers of magic mushrooms are not different in structure but also when it comes to function. So you can expect that people will differ when metabolizing drugs like psilocybin. 

Metabolism and excretion can both vary from person to person. It will be based on genetics, age, body mass, and organ condition.

The process may be based on the combination of these factors. 

1. Age

A person’s ability to metabolize psilocybin is based on his or her age. Younger people can send and remove the substance in their bloodstream than old ones. 

Those who are above 65 years old may have reduced blood flow to their liver and kidneys. It takes more time to eject it out of the body.

2. The function of Liver and Kidney

Liver enzymes help in breaking down psilocybin in the body. This enzyme function facilitates speed, and it works based on one’s genes. 

Individuals who are struggling with liver and kidney ailments need more time to allow psilocybin to pass in their system. 

3. Body Mass

This part refers to the weight and height of a person. Users who have greater body mass tend to excrete the substance faster than the ones which are lightweight even though they took the same dose.

More body fat in your body can help secrete psilocybin quicker.

4. Metabolic Rate

It is influenced by age, diet, exercise, genetics, and certain drugs a person may have taken. Fast metabolic rate means you can expel the substance quickly out of your body.

5. Intake of Water or Food

When you have a full stomach, absorbing psilocybin would be slower. You can drink a lot of water if you want to get it out of your system quicker. 

Things that Affect the High from Shrooms

After the effect kicks in, you can bask in the splendor of its effects for 3 to 6 hours. Some things create a difference in the experience of every consumer.

1. Mushroom Species

There are mushroom species that contain a higher amount of psilocybin than the others. 

2. Dose

As psilocybin varies based on the particular kind of shroom. A 0.5 gram of a certain shroom and 4 grams of another species may affect you in the same way. 

3. The Drying or Aging Process of Shrooms

Certain methods of the aging and drying process can retain more psilocybin in the shrooms. It’s how dehydrators and other kinds of moisture-removing tools work. 

Drying using a fan is not as efficient as those things.

4. Ways of Consuming Shrooms

Shrooms can be consumed in more than a single way. The common one is eating its original form.

You can mix or sprinkle its powdered or crushed form on some dishes and food. It can be taken as a capsule, tablet, or other solution as a supplement.

Needed Time for the Effects to Kick In and Duration of the Effects

As mentioned in the first part of this article, it takes 20 to 40 minutes for you to feel the effects. But some things can alter this process so some may get it after 2 hours. 

Once you feel the changes in your senses, it may last up to 3 to 6 hours. Again, it will depend on the factors mentioned above. 

The effects are not activated automatically. There’s no constant number of times as people’s physiques differ from one another.

A small dose can make you feel relaxed and euphoric. There will be changes in how you perceive colors and sounds. If you get more than the recommended dosage, the trip may last longer. 

Possible Methods to Take Psilocybin

Psilocybin was successfully separated from shrooms, making it possible for other methods. 

Oral Ingestion 

Psilocybin can be orally ingested, and it can be expelled from the body after 15 hours. 

Intravenous Injection

It has a rapid manifestation of effects when the substance is injected right through the bloodstream. It can be wiped out from the system after 6 to 7 hours.

Helpful Preparations Before Taking Shrooms

You can go over these tips to enhance your experience, and you’re ready once the effects kick in.

1. Health

It is advised that only people age 21 years old and above should take shrooms. You should be in good mental health. 

It’s not applicable if you use it when you feel depressed. Having cold and flu is not good for shroom consumption as well as a viral or bacterial infection.

You might want to be with someone who knows a lot about this thing.

2. When Having the Trip

Drink a lot of water. It’s wrong to think that it can intensify the effects when you don’t drink water.

The water left in your body will only wash the toxin, which is the chemicals from shrooms. It will leave you dehydrated, so drinking water is a simple thing to do. 

Taking shrooms with an empty stomach is the best way. You can do it at least two and a half hours after your last meal.

The effects will kick in within 20 to 60 minutes, and others may have it up to 2 hours. It all depends on your metabolism.

Talking about liquids, alcohol should be paired with psilocybin. It makes your thoughts jump into another at full speed, and it slows down your reaction at the same time.

It can cause a bad trip and dehydration too.

3. Effects Waves

When you feel like nothing is happening, never eat more than the suggested dosage. There’s no definite time for everyone to feel its effect.

You need to wait for more time. Don’t also eat more when you feel like the effects are fading.

How would you know the effects are in?

The time needed for shrooms’ effects to kick in varies from person to person. You can check the things that are mentioned above.

Observe and evaluate how your body responds to psilocybin. Then, you can expect how it will go on your next trip. 

Know thyself.

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